THE 2-MINUTE RULE FOR PHENOBARBITAL HALF GRAIN

Kramp 1978 This is the only offered possible RCT that compares barbiturate to benzodiazepine for patients with critical alcohol withdrawal. 91 patients had been randomized to obtain intramuscular diazepam vs. oral barbital (an early long-acting barbiturate). To protect blinding of physicians and patients, all patients ended up handled simultaneousl